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| Art des Jobs | Vollzeit | |
| Eingetragen am | 30.04.2024 | |
| Einsatzort | Frankfurt am Main | |
| Jobbeschreibung | The overall goal is to uncover the genomic basis of exceptional healthspans and disease tolerance in bats, understand the evolution of these traits, and identify key molecular targets for functional validation. To this end, we will assemble ~150 new reference-quality bat genomes using HiFi and HiC sequencing to better cover the diversity of bats, generate comparative transcriptomic datasets, and analyze these data using our established methods repertoire (TOGA and others). Work includes phylogenomics, performing comparative screens to identify key adaptations in coding and non-coding (miRNA) genes as well as differences in gene expression patterns across the bat phylogeny, associating genomic changes with longevity and viral reservoir status traits, identifying novel bat genes, and investigating endogenized viral elements. The exact project will be defined based on the interests of the applicants. The PhD student and postdoc will work closely with other members of the BATPROTECT team, the Hiller lab, and other Bat1K collaborators. We also offer exchanges with the other BATPROTECT labs as well as yearly retreats with all project members. |
| Qualifikationen | Your profile
- Master or PhD degree in bioinformatics/computational biology, genomics or a related area - Solid programming skills in a Linux environment, experience with shell scripts and Unix tools - Strong interest in comparative genomics, experience in comparative genomics is an advantage - English in written and oral form |
| Firma |
Senckenberg Gesellschaft für Naturforschung 60325 Frankfurt am Main |
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